There are 2 main stages of periodontal (gum) disease

STAGE 1: Gingivitis This stage is easier to treat because it only affects the gums. Left untreated, gingivitis can lead to a more serious condition known as periodontitis		Red, swollen gums Leads to periodontitis

STAGE 2: Periodontitis Periodontitis is a cascade of problems that can occur when gingivitis is left untreated. Several factors work together to cause gum disease to worsen, and could lead to surgery.	Images courtesy of Larry A. Sweeting, DDS	Bacteria cause infections Pockets, or spaces, form between tooth and gum Pocket depth increases Leads to disease progression and possibly surgery

Pockets increase in depth

Your dental professional will measure the depth of your pockets using a tiny probe. A pocket of 4 or more millimeters is a sign that you have gum disease. If you wait to treat your gum disease, it could lead to painful and expensive surgery in the future. So don't wait. Ask your dental professional how ARESTIN^® can help prevent further damage today.

Pocket depth is one indicator of the severity of periodontal disease.

A pocket depth of 4 mm or more may mean you have an infection.
A pocket depth of 7 mm or more has the highest risk of permanent damage.

Learn how to treat gum diseaseContinue

While ARESTIN^® has been demonstrated along with SRP to reduce pocket depth and bacteria in patients with periodontal disease, it has not been proven in clinical trials to reduce tooth loss.

INDICATION
ARESTIN^® is indicated as an adjunct to scaling and root planing (SRP) procedures for reduction of pocket depth in patients with adult periodontitis. ARESTIN^® may be used as part of a periodontal maintenance program, which includes good oral hygiene and SRP.

IMPORTANT SAFETY INFORMATION
ARESTIN^® should not be used in any patient who has a known sensitivity to minocycline or tetracyclines. The use of drugs of the tetracycline class during tooth development may cause permanent discoloration of the teeth, and therefore should not be used in children or in pregnant or nursing women. Hypersensitivity reactions that included, but were not limited to, anaphylaxis, angioneurotic edema, urticaria, rash, swelling of the face, and pruritus have been reported with the use of ARESTIN^®. In clinical trials, the most frequently reported nondental treatment-emergent adverse events were headache, infection, flu syndrome, and pain.

Please see full Prescribing Information

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ARESTIN^® is a registered trademark of OraPharma, Inc.

1-866-ARESTIN (1-866-273-7846)

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There are 2 main stages of periodontal (gum) disease

STAGE 1: Gingivitis

STAGE 2: Periodontitis

Pockets increase in depth