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For Dental Professionals

EASY TO ADMINISTER


How ARESTIN® is supplied and dosed

ARESTIN® (minocycline hydrochloride) Microspheres, 1 mg comes in a box with 2 trays, each containing 12 cartridges. It is packaged in a specially designed unit-dose cartridge, which is inserted into a cartridge handle for product administration. Each cartridge contains enough ARESTIN® for 1 periodontal pocket.4

ARESTIN® is easy to administer

ARESTIN® requires no preparation before administration. ARESTIN® is already premixed, premeasured, and does not require refrigeration. After scaling and root planing (SRP) procedures, ARESTIN® administration is fast and easy, with no need for local anesthesia. In 1 clinical trial, the additional time to administer a locally administered antibiotic (LAA) was less than 5 minutes per appointment.19

To administer ARESTIN®, simply follow these 6 simple steps:

Step 1

Insert the ARESTIN® cartridge into the handle while exerting slight pressure.

Step 2

Twist until you feel and hear the cartridge "lock" into place.

Step 3

Should you need to manipulate the cartridge tip to reach difficult-to-access areas, gently bend the tip, leaving the blue cap on. Bending the tip after removal of the blue cap may cause the integral plunger to rupture the cartridge wall.

Step 4

Place the cartridge tip into the periodontal pocket, parallel to the long axis of the tooth. Be sure not to force the tip into the base of the pocket.

Step 5

Gently press the thumb ring to express the ARESTIN® powder while withdrawing the cartridge tip away from the base of the pocket. If you feel any resistance during delivery, withdraw the device further.

Step 6

Once delivery is complete, retract the thumb ring and remove the ARESTIN® cartridge with your free hand. Appropriately discard the cartridge and sterilize the handle prior to reuse.

ARESTIN® does not need to be removed

Unlike other treatments, ARESTIN® Microspheres are completely bioresorbable, so you will not need to remove the powder.4

Patient instructions after treatment

Patients should be instructed to delay brushing the treated area for 12 hours after treatment with ARESTIN® and to abstain from using interproximal cleaning devices around the treated area for 10 days. Patients should also avoid hard, crunchy, or sticky foods such as popcorn or caramel that could traumatize the gingiva.